Basic Information
ID: ALA3859768
Type: Binding
Description: Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 20 to 40 mins by malachite green dye based fluorescence assay
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3859768
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 287.30 | 0.64 | 0.64 |
| 182.17 | -0.23 | -0.23 |
| 1297.30 | ||
| 532.65 | 5.45 | 5.45 |
| 533.63 | 5.71 | 5.71 |
| 381.44 | 2.24 | 2.24 |
| 541.56 | 5.37 | 5.37 |
| 641.57 | 7.13 | 7.13 |
| 505.58 | 5.10 | 5.10 |
| 574.47 | 6.40 | 6.40 |
| 555.60 | 4.84 | 4.84 |
| 593.60 | 4.49 | 4.49 |
| 641.57 | 7.13 | 7.13 |
| 537.58 | 4.51 | 4.51 |
| 621.71 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 555.60 | 4.84 | 4.84 |
| 533.63 | 5.38 | 5.38 |
| 565.63 | 5.11 | 5.11 |
| 541.56 | 5.37 | 5.37 |
| 593.60 | 4.49 | 4.49 |
| 641.64 | 5.31 | 5.31 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 555.60 | 4.84 | 4.84 |
| 605.70 | 7.40 | 7.40 |
| 437.54 | 3.80 | 3.80 |
| 537.58 | 4.51 | 4.51 |
| 663.37 | 6.62 | 6.62 |
| 535.61 | 4.26 | 4.26 |
| 589.57 | 4.17 | 4.17 |
| 565.63 | 5.11 | 5.11 |
| 533.63 | 5.71 | 5.71 |
| 619.73 | 6.32 | 6.32 |
| 621.65 | 4.67 | 4.67 |
| 604.71 | 7.14 | 7.14 |
| 489.38 | 4.02 | 4.02 |
| 535.61 | 4.26 | 4.26 |
| 595.57 | 4.91 | 4.91 |
| 621.65 | 4.67 | 4.67 |
| 535.61 | 4.26 | 4.26 |
| 595.57 | 4.91 | 4.91 |
| 641.57 | 7.13 | 7.13 |
| 517.64 | 5.22 | 5.22 |
| 574.47 | 6.40 | 6.40 |
| 593.60 | 4.49 | 4.49 |
| 565.63 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 621.71 | 5.11 | 5.11 |
| 663.37 | 6.62 | 6.62 |
| 574.47 | 6.40 | 6.40 |
| 537.58 | 4.51 | 4.51 |