Basic Information
ID: ALA3859969
Type: Functional
Description: Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated with compound followed by LPA addition by fluorescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3859969
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.60 | 6.47 | 6.47 |
| 477.60 | 6.94 | 6.94 |
| 537.66 | 6.66 | 6.66 |
| 479.55 | 5.05 | 5.05 |
| 463.58 | 6.64 | 6.64 |
| 479.58 | 6.34 | 6.34 |
| 447.53 | 4.99 | 4.99 |
| 479.58 | 6.34 | 6.34 |
| 491.58 | 5.25 | 5.25 |
| 479.58 | 6.34 | 6.34 |
| 553.66 | 7.09 | 7.09 |
| 467.54 | 6.47 | 6.47 |
| 509.60 | 6.34 | 6.34 |
| 555.63 | 6.48 | 6.48 |
| 461.56 | 4.91 | 4.91 |
| 479.55 | 5.05 | 5.05 |
| 553.66 | 7.09 | 7.09 |
| 539.63 | 6.35 | 6.35 |
| 491.58 | 5.14 | 5.14 |
| 525.60 | 6.47 | 6.47 |
| 477.56 | 4.75 | 4.75 |
| 449.55 | 6.33 | 6.33 |
| 523.63 | 6.27 | 6.27 |
| 539.63 | 6.78 | 6.78 |
| 479.55 | 5.05 | 5.05 |
| 459.54 | 5.00 | 5.00 |
| 574.07 | 7.43 | 7.43 |
| 574.07 | 7.43 | 7.43 |
| 509.60 | 6.34 | 6.34 |
| 463.53 | 4.36 | 4.36 |
| 553.66 | 7.09 | 7.09 |
| 553.66 | 7.09 | 7.09 |