Basic Information
ID: ALA3860325
Type: Binding
Description: Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3860325
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.47 | 5.44 | 5.44 |
| 327.47 | 4.10 | 4.10 |
| 356.51 | 5.66 | 5.66 |
| 356.51 | 5.66 | 5.66 |
| 312.45 | 5.25 | 5.25 |
| 356.51 | 5.66 | 5.66 |
| 356.51 | 5.66 | 5.66 |
| 426.60 | 6.66 | 6.66 |
| 314.47 | 5.44 | 5.44 |
| 426.60 | 6.66 | 6.66 |
| 398.54 | 5.88 | 5.88 |