Basic Information
ID: ALA3860489
Type: Binding
Description: Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPH
Format: BAO_0000019
Organism: Bos taurus
Target: Dihydrofolate reductase(ALA1075051)
Document: ALA3860041
Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3860489
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 554.62 | 4.74 | 4.74 |
| 524.60 | 4.73 | 4.73 |
| 482.99 | 5.67 | 5.67 |
| 508.60 | 5.03 | 5.03 |
| 402.52 | 5.30 | 5.30 |
| 529.01 | 5.37 | 5.37 |
| 482.99 | 5.67 | 5.67 |
| 422.94 | 5.65 | 5.65 |
| 498.99 | 5.37 | 5.37 |
| 468.96 | 5.36 | 5.36 |
| 524.60 | 4.73 | 4.73 |
| 448.54 | 4.76 | 4.76 |
| 418.52 | 5.00 | 5.00 |
| 468.96 | 5.36 | 5.36 |
| 448.54 | 5.01 | 5.01 |
| 494.57 | 4.72 | 4.72 |
| 478.57 | 5.02 | 5.02 |
| 402.52 | 5.05 | 5.05 |
| 388.49 | 5.00 | 5.00 |
| 422.94 | 5.65 | 5.65 |
| 408.91 | 5.34 | 5.34 |
| 478.57 | 5.02 | 5.02 |
| 503.41 | 6.01 | 6.01 |
| 508.60 | 5.03 | 5.03 |
| 448.54 | 5.01 | 5.01 |
| 464.54 | 4.71 | 4.71 |
| 438.94 | 5.35 | 5.35 |
| 498.99 | 5.37 | 5.37 |
| 494.57 | 4.72 | 4.72 |
| 482.99 | 5.42 | 5.42 |
| 422.94 | 5.40 | 5.40 |
| 418.52 | 5.00 | 5.00 |
| 443.36 | 5.99 | 5.99 |
| 448.54 | 5.01 | 5.01 |
| 438.94 | 5.35 | 5.35 |
| 529.01 | 5.37 | 5.37 |
| 462.57 | 5.32 | 5.32 |
| 434.52 | 4.70 | 4.70 |
| 468.96 | 5.36 | 5.36 |
| 508.60 | 4.78 | 4.78 |
| 464.54 | 4.71 | 4.71 |
| 462.57 | 5.07 | 5.07 |