Basic Information
ID: ALA3861711
Type: Binding
Description: Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine influx by measuring ratio of rhodamine mean fluorescence intensity in presence and absence of compound at 10 uM incubated for 20 mins by flow cytometry
Organism: Homo sapiens
Cell type: K562R
Activity Charts
Bioactivity
Activity Types for Assay ALA3861711
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 810.99 | 3.99 | 3.99 |
| 1202.63 | ||
| 778.95 | 4.75 | 4.75 |
| 930.11 | 5.08 | 5.08 |
| 916.08 | 4.83 | 4.83 |
| 948.13 | 4.75 | 4.75 |
| 941.92 | 5.62 | 5.62 |
| 887.04 | 4.83 | 4.83 |
| 964.13 | 5.62 | 5.62 |
| 939.12 | 6.42 | 6.42 |
| 996.17 | 5.54 | 5.54 |
| 941.13 | 6.16 | 6.16 |
| 879.06 | 4.98 | 4.98 |
| 972.15 | 4.73 | 4.73 |
| 877.05 | 5.24 | 5.24 |