Assay Report Card

Basic Information

ID: ALA3861713

Type: Binding

Description: Inhibition of P-gp in doxorubicin-resistant human K562R cells assessed as rhodamine efflux by measuring ratio of mean fluorescence intensity in presence and absence of compound at 10 uM incubated for 1 hr by flow cytometry

Organism: Homo sapiens

Cell type: K562R

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
454.615.095.09
810.993.993.99
1202.63
778.954.754.75
930.115.085.08
916.084.834.83
948.134.754.75
941.925.625.62
887.044.834.83
964.135.625.62
939.126.426.42
996.175.545.54
941.136.166.16
879.064.984.98
972.154.734.73
877.055.245.24