Basic Information
ID: ALA3862350
Type: Binding
Description: Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuring turbidity preincubated for 30 mins followed by lowering pH from 7.2 to 4.4 measured after 72 hrs by microplate spectrophotometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3862350
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.99 | 5.38 | 5.38 |
| 776.87 | 4.56 | 4.56 |
| 308.12 | 4.50 | 4.50 |
| 252.65 | 3.70 | 3.70 |
| 252.65 | 3.70 | 3.70 |
| 310.33 | 3.32 | 3.32 |