Basic Information
ID: ALA3862619
Type: Binding
Description: Inhibition of TNFalpha-induced NFkappaB activation in mouse NIH-3T3 cells expressing NFkappaB (unknown origin) preincubated for 15 mins followed by TNFalpha addition measured after 6 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: NIH3T3
Activity Charts
Bioactivity
Activity Types for Assay ALA3862619
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.31 | 2.16 | 2.16 |
| 306.49 | 5.17 | 5.17 |
| 424.63 | 6.96 | 6.96 |
| 302.46 | 5.11 | 5.11 |
| 446.72 | 8.47 | 8.47 |
| 322.49 | 4.38 | 4.38 |
| 364.53 | 4.95 | 4.95 |
| 306.49 | 5.17 | 5.17 |
| 316.44 | 4.63 | 4.63 |
| 290.49 | 5.96 | 5.96 |
| 436.64 | 7.43 | 7.43 |
| 410.60 | 7.03 | 7.03 |
| 364.53 | 4.95 | 4.95 |
| 348.53 | 5.74 | 5.74 |
| 304.47 | 5.38 | 5.38 |