Basic Information
ID: ALA3862723
Type: Binding
Description: Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 substrate incubated for 30 mins by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Aurora-A(ALA4722)
Document: ALA3861974
Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 substrate incubated for 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3862723
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.93 | 5.75 | 5.75 |
| 461.95 | 5.71 | 5.71 |
| 318.26 | 3.21 | 3.21 |
| 264.29 | 2.21 | 2.21 |
| 461.55 | 4.28 | 4.28 |
| 266.26 | 1.90 | 1.90 |
| 482.57 | 4.80 | 4.80 |
| 307.31 | 1.55 | 1.55 |
| 458.54 | 5.32 | 5.32 |
| 329.16 | 2.96 | 2.96 |
| 351.48 | 4.61 | 4.61 |
| 284.71 | 2.85 | 2.85 |
| 415.52 | 5.02 | 5.02 |
| 323.42 | 3.93 | 3.93 |
| 438.51 | 3.68 | 3.68 |
| 352.46 | 3.35 | 3.35 |
| 266.26 | 1.90 | 1.90 |
| 264.29 | 2.50 | 2.50 |
| 459.53 | 4.71 | 4.71 |
| 294.27 | 1.89 | 1.89 |
| 309.39 | 3.54 | 3.54 |
| 340.45 | 3.03 | 3.03 |
| 409.52 | 3.17 | 3.17 |
| 323.42 | 3.88 | 3.88 |
| 284.71 | 2.85 | 2.85 |
| 424.48 | 3.29 | 3.29 |
| 337.45 | 4.27 | 4.27 |
| 337.45 | 4.44 | 4.44 |
| 363.36 | 4.33 | 4.33 |
| 338.44 | 3.46 | 3.46 |
| 367.47 | 3.89 | 3.89 |
| 264.29 | 2.21 | 2.21 |
| 266.26 | 1.90 | 1.90 |
| 374.26 | 4.08 | 4.08 |
| 295.37 | 3.32 | 3.32 |
| 337.45 | 4.27 | 4.27 |
| 319.15 | 3.50 | 3.50 |
| 266.26 | 1.90 | 1.90 |
| 351.48 | 4.66 | 4.66 |
| 405.57 | 5.83 | 5.83 |
| 294.27 | 1.89 | 1.89 |
| 444.56 | 5.11 | 5.11 |
| 250.26 | 2.20 | 2.20 |
| 264.29 | 2.50 | 2.50 |
| 307.31 | 1.55 | 1.55 |
| 414.53 | 5.62 | 5.62 |
| 323.42 | 3.88 | 3.88 |
| 323.42 | 3.88 | 3.88 |
| 452.54 | 4.07 | 4.07 |
| 352.46 | 3.35 | 3.35 |