Basic Information
ID: ALA3862791
Type: Binding
Description: Inhibition of Escherichia coli DNA gyrase B ATP binding site assessed as reduction in supercoiling of relaxed pNO1 DNA after 30 mins in presence of biotinylated oligonucleotide by sybrGOLD staining based fluorescence assay
Format: BAO_0000357
Organism: Escherichia coli
Target: DNA gyrase subunit B(ALA1826)
Document: ALA3861980
Inhibition of Escherichia coli DNA gyrase B ATP binding site assessed as reduction in supercoiling of relaxed pNO1 DNA after 30 mins in presence of biotinylated oligonucleotide by sybrGOLD staining based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3862791
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 612.63 | 3.63 | 3.63 |
| 516.17 | 3.90 | 3.90 |
| 488.12 | 3.42 | 3.42 |
| 516.17 | 4.21 | 4.21 |
| 530.20 | 4.29 | 4.29 |
| 427.27 | 3.99 | 3.99 |
| 488.12 | 3.42 | 3.42 |
| 413.24 | 3.60 | 3.60 |
| 427.27 | 3.69 | 3.69 |
| 427.27 | 3.69 | 3.69 |
| 530.20 | 4.29 | 4.29 |
| 399.22 | 3.21 | 3.21 |
| 516.17 | 3.90 | 3.90 |
| 516.17 | 3.90 | 3.90 |
| 502.14 | 3.81 | 3.81 |
| 416.10 | 3.98 | 3.98 |
| 441.30 | 4.08 | 4.08 |
| 427.27 | 3.69 | 3.69 |
| 516.17 | 3.90 | 3.90 |
| 427.27 | 3.69 | 3.69 |
| 516.17 | 4.21 | 4.21 |
| 327.20 | 3.77 | 3.77 |