Assay Report Card

Basic Information

ID: ALA3863087

Type: ADME

Description: Selectivity ratio of EC50 for human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as inhibition of agonist induced calcium mobilization to EC50 for alpha1A adrenergic receptor (unknown origin) assessed as inhibition of agonist induced effect

Organism: Homo sapiens

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
387.441.061.06
408.522.342.34
483.634.094.09
456.973.563.56
456.973.563.56
441.553.073.07
485.024.344.34
450.562.532.53
438.983.423.42
464.582.782.78
455.583.313.31