Basic Information
ID: ALA3863087
Type: ADME
Description: Selectivity ratio of EC50 for human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as inhibition of agonist induced calcium mobilization to EC50 for alpha1A adrenergic receptor (unknown origin) assessed as inhibition of agonist induced effect
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: ADMET(ALA612558)
Document: ALA3861996
Selectivity ratio of EC50 for human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as inhibition of agonist induced calcium mobilization to EC50 for alpha1A adrenergic receptor (unknown origin) assessed as inhibition of agonist induced effect: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3863087
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.44 | 1.06 | 1.06 |
| 408.52 | 2.34 | 2.34 |
| 483.63 | 4.09 | 4.09 |
| 456.97 | 3.56 | 3.56 |
| 456.97 | 3.56 | 3.56 |
| 441.55 | 3.07 | 3.07 |
| 485.02 | 4.34 | 4.34 |
| 450.56 | 2.53 | 2.53 |
| 438.98 | 3.42 | 3.42 |
| 464.58 | 2.78 | 2.78 |
| 455.58 | 3.31 | 3.31 |