Basic Information
ID: ALA3863728
Type: Binding
Description: Inhibition of HDAC in human HeLa cell nuclear extracts at 20 uM preincubated for 5 mins followed by Boc-Lys(Ac)-AMC substrate addition measured after 30 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Unchecked(ALA612545)
Document: ALA3862022
Inhibition of HDAC in human HeLa cell nuclear extracts at 20 uM preincubated for 5 mins followed by Boc-Lys(Ac)-AMC substrate addition measured after 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3863728
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.46 | 1.54 | 1.54 |
| 479.61 | 3.71 | 3.71 |
| 625.68 | 5.90 | 5.90 |
| 541.69 | 5.00 | 5.00 |
| 569.74 | 5.32 | 5.32 |
| 591.75 | 6.15 | 6.15 |
| 521.70 | 4.73 | 4.73 |
| 576.13 | 5.65 | 5.65 |
| 555.71 | 4.93 | 4.93 |
| 586.68 | 4.91 | 4.91 |