Basic Information
ID: ALA3863877
Type: Functional
Description: Antagonist activity at human 5-HT2BR expressed in Flp-In HEK cells assessed as inhibition of 5-HT-induced calcium mobilization preincubated for 5 to 10 mins followed 5-HT addition by Fluo-4 dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3863877
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.33 | 1.77 | 1.77 |
| 294.15 | 3.27 | 3.27 |
| 405.89 | 1.36 | 1.36 |
| 447.92 | 1.93 | 1.93 |
| 433.90 | 1.54 | 1.54 |
| 432.91 | 1.11 | 1.11 |