Assay Report Card

Basic Information

ID: ALA3863939

Type: Binding

Description: Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as protection of cell membrane integrity pre-treated with compound for 1 hr followed by Stx exposure for 24 hrs by LDH release assay relative to untreated control

Organism: Shigella dysenteriae

Cell type: Vero

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
151.13-0.77-0.77
136.110.060.06
257.263.283.28
292.452.552.55
265.313.543.54
345.422.712.71