Assay Report Card

Basic Information

ID: ALA3864044

Type: ADME

Description: Drug metabolism in Escherichia coli membranes expressing recombinant CYP2C18 (unknown origin) co-expressed with human NADPH-CPR/bacterial GroEL/GroES assessed as CYP2C18-mediated R-(+)- N-((1-hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4-(2-hydroxypropan-2-yl)furan-2-sulfonamide formation at 10 to 100 uM after 120 mins by LC-MS/MS analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
404.492.992.99