ID: ALA3864044
Type: ADME
Description: Drug metabolism in Escherichia coli membranes expressing recombinant CYP2C18 (unknown origin) co-expressed with human NADPH-CPR/bacterial GroEL/GroES assessed as CYP2C18-mediated R-(+)- N-((1-hydroxy-1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4-(2-hydroxypropan-2-yl)furan-2-sulfonamide formation at 10 to 100 uM after 120 mins by LC-MS/MS analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3864044
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
404.49 | 2.99 | 2.99 |