Basic Information
ID: ALA3864311
Type: Binding
Description: Inhibition of SENP1 catalytic domain (419 to 644 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in deSUMOylation preincubated for 10 mins followed by addition of RanGAP-SUMO as substrate measured after 25 mins by coomassie staining-based SDS-PAGE analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3864311
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.76 | 3.34 | 3.34 |
| 390.45 | 2.11 | 2.11 |
| 432.52 | 5.94 | 5.94 |
| 513.44 | 6.62 | 6.62 |
| 359.36 | 3.16 | 3.16 |
| 485.38 | 6.30 | 6.30 |
| 464.57 | 5.77 | 5.77 |
| 511.42 | 6.70 | 6.70 |
| 561.46 | 7.56 | 7.56 |
| 365.46 | 3.18 | 3.18 |
| 462.55 | 5.85 | 5.85 |
| 307.31 | 2.16 | 2.16 |
| 462.55 | 5.94 | 5.94 |
| 434.54 | 5.85 | 5.85 |
| 415.52 | 5.58 | 5.58 |
| 451.31 | 6.76 | 6.76 |
| 412.51 | 5.48 | 5.48 |
| 386.48 | 5.08 | 5.08 |
| 406.49 | 5.42 | 5.42 |
| 511.42 | 6.70 | 6.70 |
| 457.56 | 4.77 | 4.77 |
| 464.57 | 5.86 | 5.86 |
| 433.38 | 3.52 | 3.52 |
| 543.80 | 4.12 | 4.12 |
| 406.49 | 5.42 | 5.42 |