Basic Information
ID: ALA3864977
Type: Binding
Description: Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3864977
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 610.85 | 5.21 | 5.21 |
| 393.54 | 2.39 | 2.39 |
| 520.72 | 4.07 | 4.07 |
| 528.54 | 5.04 | 5.04 |
| 437.55 | 2.91 | 2.91 |
| 302.43 | 1.09 | 1.09 |
| 392.55 | 3.00 | 3.00 |
| 422.58 | 3.01 | 3.01 |
| 452.60 | 3.02 | 3.02 |
| 406.58 | 3.04 | 3.04 |
| 393.54 | 2.39 | 2.39 |
| 460.55 | 4.02 | 4.02 |
| 496.66 | 4.23 | 4.23 |
| 398.60 | 3.38 | 3.38 |
| 437.55 | 2.91 | 2.91 |