Basic Information
ID: ALA3865206
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM up to 15 mins in presence of NADPH by LC-MS-MS analysis
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Liver
Target: ADMET(ALA612558)
Document: ALA3864167
Intrinsic clearance in human liver microsomes at 1 uM up to 15 mins in presence of NADPH by LC-MS-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3865206
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.50 | 5.09 | 5.09 |
| 385.51 | 4.98 | 4.98 |
| 400.53 | 4.76 | 4.76 |
| 404.49 | 5.22 | 5.22 |
| 404.49 | 5.22 | 5.22 |
| 414.55 | 5.07 | 5.07 |
| 405.48 | 4.62 | 4.62 |
| 365.48 | 3.57 | 3.57 |
| 413.52 | 4.89 | 4.89 |
| 434.52 | 5.23 | 5.23 |
| 474.55 | 5.49 | 5.49 |
| 400.53 | 5.39 | 5.39 |
| 399.54 | 5.37 | 5.37 |
| 435.52 | 5.65 | 5.65 |
| 418.52 | 4.90 | 4.90 |
| 404.49 | 5.22 | 5.22 |
| 410.56 | 4.62 | 4.62 |
| 417.53 | 5.15 | 5.15 |
| 399.54 | 5.37 | 5.37 |
| 404.49 | 5.22 | 5.22 |
| 378.52 | 5.08 | 5.08 |
| 434.97 | 5.42 | 5.42 |
| 379.55 | 4.86 | 4.86 |
| 468.52 | 5.78 | 5.78 |
| 387.49 | 4.48 | 4.48 |
| 416.53 | 5.09 | 5.09 |
| 474.55 | 5.84 | 5.84 |
| 389.50 | 4.48 | 4.48 |
| 388.51 | 5.09 | 5.09 |
| 397.54 | 5.00 | 5.00 |
| 400.53 | 4.76 | 4.76 |
| 410.54 | 3.58 | 3.58 |
| 404.49 | 5.22 | 5.22 |
| 401.51 | 4.16 | 4.16 |
| 416.53 | 5.09 | 5.09 |
| 418.52 | 4.90 | 4.90 |
| 458.48 | 5.37 | 5.37 |
| 383.47 | 3.71 | 3.71 |
| 416.53 | 5.09 | 5.09 |
| 367.50 | 4.33 | 4.33 |
| 413.52 | 5.01 | 5.01 |
| 492.54 | 5.63 | 5.63 |
| 444.46 | 5.70 | 5.70 |
| 418.52 | 4.90 | 4.90 |
| 434.97 | 5.42 | 5.42 |
| 429.56 | 5.38 | 5.38 |
| 400.52 | 5.80 | 5.80 |
| 404.49 | 5.22 | 5.22 |
| 488.51 | 5.38 | 5.38 |
| 409.57 | 4.98 | 4.98 |
| 430.55 | 4.77 | 4.77 |
| 399.54 | 5.01 | 5.01 |
| 436.51 | 5.04 | 5.04 |
| 400.53 | 4.76 | 4.76 |
| 411.51 | 4.96 | 4.96 |
| 422.48 | 5.36 | 5.36 |
| 416.53 | 5.09 | 5.09 |
| 394.52 | 4.45 | 4.45 |
| 468.52 | 5.78 | 5.78 |
| 309.41 | 3.77 | 3.77 |
| 337.47 | 4.19 | 4.19 |
| 391.54 | 4.68 | 4.68 |
| 399.54 | 5.37 | 5.37 |
| 400.53 | 4.76 | 4.76 |
| 413.57 | 5.71 | 5.71 |
| 417.53 | 5.15 | 5.15 |
| 399.54 | 5.37 | 5.37 |
| 400.53 | 4.76 | 4.76 |
| 403.53 | 4.10 | 4.10 |
| 430.55 | 4.77 | 4.77 |
| 436.54 | 4.27 | 4.27 |
| 385.51 | 4.81 | 4.81 |
| 401.51 | 4.16 | 4.16 |
| 400.53 | 4.76 | 4.76 |
| 422.48 | 5.36 | 5.36 |
| 385.51 | 5.50 | 5.50 |
| 457.50 | 5.98 | 5.98 |
| 370.50 | 4.78 | 4.78 |
| 418.52 | 4.90 | 4.90 |
| 461.51 | 5.56 | 5.56 |
| 352.48 | 4.02 | 4.02 |
| 465.40 | 5.85 | 5.85 |
| 364.53 | 4.88 | 4.88 |
| 484.52 | 6.03 | 6.03 |
| 400.53 | 4.76 | 4.76 |
| 379.50 | 3.91 | 3.91 |
| 396.54 | 4.70 | 4.70 |
| 418.52 | 4.90 | 4.90 |
| 399.54 | 5.37 | 5.37 |
| 371.48 | 4.42 | 4.42 |
| 378.52 | 4.41 | 4.41 |
| 402.54 | 4.76 | 4.76 |
| 464.59 | 4.49 | 4.49 |
| 393.53 | 3.32 | 3.32 |
| 404.49 | 5.22 | 5.22 |
| 366.51 | 4.93 | 4.93 |
| 434.97 | 5.42 | 5.42 |