Basic Information
ID: ALA3865237
Type: Binding
Description: Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Ser473 after 60 mins by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PC-3
Target: PI3-kinase p110-beta subunit(ALA3145)
Document: ALA3864168
Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Ser473 after 60 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3865237
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 517.53 | 2.56 | 2.56 |
| 540.61 | 2.54 | 2.54 |
| 513.52 | 3.51 | 3.51 |
| 526.59 | 2.20 | 2.20 |
| 452.44 | 2.07 | 2.07 |
| 433.43 | 2.89 | 2.89 |
| 457.46 | 4.34 | 4.34 |
| 477.49 | 2.40 | 2.40 |
| 504.56 | 2.97 | 2.97 |
| 519.50 | 2.56 | 2.56 |
| 434.42 | 3.49 | 3.49 |
| 450.42 | 2.67 | 2.67 |
| 405.42 | 3.37 | 3.37 |
| 528.54 | 3.20 | 3.20 |
| 456.47 | 4.18 | 4.18 |