Basic Information
ID: ALA3866777
Type: Binding
Description: Inhibition of GTPgammaS-induced activation of GIRK1/4 (unknown origin) expressed in HEK293 cells assessed as decrease in channel current at 10 uM after 2 mins at -40 mV holding potential by automated patch-clamp electrophysiology assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3866777
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 620.69 | 2.88 | 2.88 |
| 813.85 | 3.02 | 3.02 |
| 668.78 | 4.24 | 4.24 |
| 606.67 | 2.63 | 2.63 |
| 755.81 | 3.33 | 3.33 |
| 492.65 | 3.63 | 3.63 |
| 736.81 | 2.39 | 2.39 |
| 826.89 | 3.87 | 3.87 |
| 826.89 | 4.01 | 4.01 |
| 747.84 | 4.53 | 4.53 |
| 840.92 | 4.26 | 4.26 |
| 692.76 | 2.64 | 2.64 |
| 682.76 | 4.17 | 4.17 |
| 654.71 | 3.54 | 3.54 |
| 678.73 | 2.25 | 2.25 |
| 684.74 | 2.73 | 2.73 |
| 789.88 | 5.26 | 5.26 |
| 827.88 | 3.26 | 3.26 |
| 722.78 | 2.15 | 2.15 |
| 841.90 | 3.65 | 3.65 |
| 696.79 | 4.56 | 4.56 |