Basic Information
ID: ALA3867165
Type: Functional
Description: Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Organism: Homo sapiens
Cell type: Neutrophil
Activity Charts
Bioactivity
Activity Types for Assay ALA3867165
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 122.12 | 1.20 | 1.20 |
| 456.54 | 5.48 | 5.48 |
| 350.41 | 4.19 | 4.19 |
| 480.52 | 6.27 | 6.27 |
| 482.53 | 5.72 | 5.72 |
| 478.50 | 6.81 | 6.81 |
| 454.52 | 5.46 | 5.46 |
| 274.32 | 2.90 | 2.90 |
| 228.29 | 3.19 | 3.19 |
| 272.30 | 2.88 | 2.88 |
| 270.28 | 3.42 | 3.42 |
| 244.29 | 2.89 | 2.89 |
| 576.86 | 5.85 | 5.85 |
| 258.32 | 3.19 | 3.19 |
| 242.27 | 2.87 | 2.87 |
| 254.24 | 2.45 | 2.45 |
| 270.28 | 3.42 | 3.42 |
| 415.43 | 3.75 | 3.75 |
| 346.38 | 4.71 | 4.71 |
| 726.73 | -2.00 | -2.00 |
| 484.55 | 5.74 | 5.74 |
| 480.52 | 6.27 | 6.27 |
| 484.55 | 5.74 | 5.74 |
| 300.31 | 3.43 | 3.43 |
| 348.40 | 4.17 | 4.17 |
| 152.19 | 1.93 | 1.93 |
| 482.53 | 5.72 | 5.72 |
| 376.41 | 4.72 | 4.72 |
| 542.58 | 5.74 | 5.74 |
| 302.33 | 2.89 | 2.89 |
| 470.57 | 5.79 | 5.79 |
| 508.53 | 6.81 | 6.81 |
| 350.41 | 4.19 | 4.19 |
| 512.56 | 5.73 | 5.73 |
| 538.55 | 6.82 | 6.82 |
| 350.41 | 4.19 | 4.19 |
| 456.54 | 5.48 | 5.48 |
| 588.66 | 7.02 | 7.02 |
| 348.40 | 4.17 | 4.17 |
| 376.41 | 4.72 | 4.72 |
| 538.55 | 6.82 | 6.82 |