Basic Information
ID: ALA3867191
Type: ADME
Description: Reversible inhibition of CYP2C9 in human liver microsomes using (S)-warfarin as substrate in presence of NADPH by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3867191
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.87 | 4.21 | 4.21 |
| 391.52 | 3.93 | 3.93 |
| 402.48 | 1.96 | 1.96 |
| 367.43 | 3.24 | 3.24 |
| 429.55 | 2.17 | 2.17 |
| 381.46 | 3.54 | 3.54 |
| 382.45 | 2.82 | 2.82 |
| 392.44 | 3.59 | 3.59 |
| 393.47 | 3.14 | 3.14 |
| 408.48 | 2.72 | 2.72 |
| 408.48 | 2.84 | 2.84 |
| 399.52 | 3.41 | 3.41 |
| 427.43 | 3.60 | 3.60 |
| 427.43 | 3.38 | 3.38 |
| 378.45 | 3.66 | 3.66 |
| 460.44 | 3.74 | 3.74 |
| 429.40 | 3.26 | 3.26 |
| 425.47 | 2.76 | 2.76 |
| 426.56 | 2.94 | 2.94 |
| 329.38 | 1.90 | 1.90 |
| 407.45 | 3.17 | 3.17 |
| 372.47 | 3.33 | 3.33 |
| 386.50 | 3.14 | 3.14 |
| 406.49 | 1.77 | 1.77 |
| 413.41 | 3.60 | 3.60 |
| 401.53 | 4.06 | 4.06 |
| 412.53 | 2.55 | 2.55 |
| 398.49 | 3.18 | 3.18 |
| 428.49 | 3.77 | 3.77 |
| 398.51 | 2.16 | 2.16 |
| 416.52 | 2.77 | 2.77 |
| 487.65 | 3.86 | 3.86 |
| 400.48 | 2.13 | 2.13 |
| 386.50 | 3.14 | 3.14 |
| 408.51 | 2.09 | 2.09 |
| 385.46 | 3.59 | 3.59 |
| 425.56 | 3.12 | 3.12 |
| 370.50 | 2.78 | 2.78 |
| 385.51 | 2.72 | 2.72 |
| 384.48 | 3.10 | 3.10 |
| 412.53 | 2.29 | 2.29 |
| 217.27 | 1.95 | 1.95 |
| 348.41 | 2.73 | 2.73 |
| 372.47 | 2.75 | 2.75 |
| 405.50 | 2.75 | 2.75 |
| 410.44 | 3.08 | 3.08 |
| 428.53 | 3.49 | 3.49 |
| 398.51 | 3.29 | 3.29 |
| 386.50 | 3.14 | 3.14 |
| 422.53 | 2.40 | 2.40 |
| 372.47 | 3.33 | 3.33 |
| 409.49 | 2.65 | 2.65 |
| 390.53 | 3.45 | 3.45 |
| 330.37 | 1.14 | 1.14 |
| 374.49 | 2.92 | 2.92 |
| 257.34 | 2.87 | 2.87 |
| 384.52 | 3.17 | 3.17 |
| 426.56 | 2.94 | 2.94 |
| 385.47 | 2.50 | 2.50 |
| 408.51 | 2.09 | 2.09 |
| 358.44 | 2.37 | 2.37 |
| 251.29 | 2.49 | 2.49 |
| 384.48 | 3.33 | 3.33 |
| 400.48 | 2.13 | 2.13 |
| 390.49 | 3.05 | 3.05 |
| 404.50 | 2.13 | 2.13 |
| 442.45 | 3.19 | 3.19 |