Basic Information
ID: ALA3867199
Type: ADME
Description: Time dependent inhibition of CYP3A4 in human liver microsomes assessed as substrate AUC shift using midazolam as substrate
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3867199
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.43 | 3.24 | 3.24 |
| 382.45 | 2.82 | 2.82 |
| 392.44 | 3.59 | 3.59 |
| 393.47 | 3.14 | 3.14 |
| 427.43 | 3.60 | 3.60 |
| 429.40 | 3.26 | 3.26 |
| 413.41 | 3.60 | 3.60 |
| 400.48 | 2.13 | 2.13 |
| 442.45 | 3.19 | 3.19 |