Basic Information
ID: ALA3867372
Type: Binding
Description: Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADPH measured after 60 mins by resazurin/diaphorase coupled assay
Organism: Toxoplasma gondii
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA3867372
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 454.45 | 0.27 | 0.27 |
| 394.40 | 2.01 | 2.01 |
| 293.16 | 3.52 | 3.52 |
| 399.50 | 2.81 | 2.81 |
| 273.73 | 2.45 | 2.45 |
| 265.32 | 2.67 | 2.67 |
| 409.93 | 2.99 | 2.99 |
| 374.49 | 2.94 | 2.94 |
| 352.35 | 2.98 | 2.98 |
| 352.36 | 1.98 | 1.98 |
| 279.13 | 3.51 | 3.51 |
| 366.34 | 4.02 | 4.02 |
| 413.49 | 2.45 | 2.45 |
| 350.81 | 3.36 | 3.36 |
| 423.91 | 2.63 | 2.63 |
| 339.23 | 2.27 | 2.27 |
| 346.44 | 2.63 | 2.63 |
| 388.48 | 2.58 | 2.58 |
| 260.68 | 2.15 | 2.15 |
| 383.38 | 4.33 | 4.33 |
| 383.38 | 4.33 | 4.33 |
| 492.93 | 4.21 | 4.21 |
| 279.35 | 2.68 | 2.68 |