Basic Information
ID: ALA3867385
Type: Binding
Description: Inhibition of N-terminal 6xHis-tagged human TDO expressed in Escherichia cli Rosetta (DE3) pLysS using L-tryptophan as substrate preincubated for 1 hr measured after 15 mins in presence of bovine liver and methylene blue by spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3867385
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.64 | 1.69 | 1.69 |
| 348.72 | 2.17 | 2.17 |
| 318.74 | 3.83 | 3.83 |
| 315.72 | 0.97 | 0.97 |
| 320.71 | 2.38 | 2.38 |
| 284.29 | 3.17 | 3.17 |
| 313.32 | 2.02 | 2.02 |
| 302.28 | 3.31 | 3.31 |
| 303.27 | 2.59 | 2.59 |
| 304.26 | 1.86 | 1.86 |
| 332.27 | 1.66 | 1.66 |
| 314.69 | 1.10 | 1.10 |
| 319.73 | 3.10 | 3.10 |