Basic Information
ID: ALA3867651
Type: ADME
Description: Antagonist activity at alpha1B-adrenoceptor in Wistar rat spleen assessed as inhibition of phenylphrine-induced contractions measured after 30 mins in presence of (+/-)-propranolol hydrochloride
Organism: Rattus norvegicus
Strain: Wistar
Activity Charts
Bioactivity
Activity Types for Assay ALA3867651
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.41 | 3.06 | 3.06 |
| 340.42 | 2.79 | 2.79 |
| 370.49 | 3.47 | 3.47 |
| 354.45 | 3.18 | 3.18 |
| 384.52 | 3.86 | 3.86 |
| 340.47 | 3.46 | 3.46 |
| 368.48 | 3.57 | 3.57 |
| 354.49 | 3.85 | 3.85 |
| 340.47 | 3.46 | 3.46 |
| 324.47 | 3.84 | 3.84 |