Basic Information
ID: ALA3868064
Type: Binding
Description: Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition after 30 mins by HTRF assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK3(ALA2148)
Document: ALA3867460
Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by substrate addition after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3868064
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 464.45 | 4.93 | 4.93 |
| 403.44 | 4.88 | 4.88 |
| 498.51 | 5.86 | 5.86 |
| 386.46 | 4.78 | 4.78 |
| 375.38 | 4.41 | 4.41 |
| 501.58 | 3.41 | 3.41 |
| 455.54 | 2.63 | 2.63 |
| 457.54 | 3.03 | 3.03 |
| 403.44 | 4.88 | 4.88 |
| 469.57 | 2.94 | 2.94 |
| 483.59 | 3.27 | 3.27 |
| 444.50 | 3.12 | 3.12 |
| 468.58 | 2.55 | 2.55 |
| 491.52 | 7.01 | 7.01 |
| 411.47 | 4.65 | 4.65 |
| 478.50 | 2.96 | 2.96 |
| 386.41 | 4.46 | 4.46 |