ID: ALA3868074
Type: Binding
Description: Inhibition of recombinant CYP21 (unknown origin) overexpressed in human AD293 cells assessed as reduction in 11-deoxycortisol formation preincubated for 60 mins followed by addition of 17-alpha-hydroxyprogesterone as substrate measured after 45 mins by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: AD293
Bioactivity
Activity Types for Assay ALA3868074
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
531.44 | 4.21 | 4.21 |
633.56 | 3.78 | 3.78 |
595.55 | 4.40 | 4.40 |
581.52 | 4.01 | 4.01 |
593.53 | 4.15 | 4.15 |
637.59 | 4.17 | 4.17 |
621.47 | 4.51 | 4.51 |
592.51 | 3.51 | 3.51 |
635.60 | 5.11 | 5.11 |
611.55 | 3.64 | 3.64 |
603.48 | 4.21 | 4.21 |
645.59 | 2.99 | 2.99 |
567.50 | 3.62 | 3.62 |