Assay Report Card

Basic Information

ID: ALA3868074

Type: Binding

Description: Inhibition of recombinant CYP21 (unknown origin) overexpressed in human AD293 cells assessed as reduction in 11-deoxycortisol formation preincubated for 60 mins followed by addition of 17-alpha-hydroxyprogesterone as substrate measured after 45 mins by LC-MS/MS analysis

Organism: Homo sapiens

Cell type: AD293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
531.444.214.21
633.563.783.78
595.554.404.40
581.524.014.01
593.534.154.15
637.594.174.17
621.474.514.51
592.513.513.51
635.605.115.11
611.553.643.64
603.484.214.21
645.592.992.99
567.503.623.62