Basic Information
ID: ALA3868318
Type: Binding
Description: Displacement of [3H]-epibatidine from alpha4beta2-nACHR in rat cerebral cortex membranes preincubated for 30 mins followed by overnight incubation with [3H]-epibatine
Format: BAO_0000249
Organism: Rattus norvegicus
Tissue: Cerebral cortex
Subcellular Fraction: Membrane
Target: Neuronal acetylcholine receptor; alpha4/beta2(ALA1907596)
Document: ALA3867476
Displacement of [3H]-epibatidine from alpha4beta2-nACHR in rat cerebral cortex membranes preincubated for 30 mins followed by overnight incubation with [3H]-epibatine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3868318
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 221.30 | 2.17 | 2.17 |
| 315.17 | 2.83 | 2.83 |
| 236.27 | 2.07 | 2.07 |
| 287.40 | 2.67 | 2.67 |
| 312.37 | 3.73 | 3.73 |
| 332.40 | 2.58 | 2.58 |
| 303.40 | 2.38 | 2.38 |
| 283.37 | 3.53 | 3.53 |
| 328.37 | 3.44 | 3.44 |
| 286.17 | 2.63 | 2.63 |
| 299.37 | 3.24 | 3.24 |