Basic Information
ID: ALA3868337
Type: Functional
Description: Antagonist activity at rat OX1 receptor assessed as inhibition of Ala-6,12 orexin-A-induced calcium increase preincubated for 5 mins prior to Ala-6,12 orexin-A addition measured at 1 sec intervals for 1 min by Fluo-4AM dye-based FLIPR assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3868337
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.43 | 3.74 | 3.74 |
| 408.41 | 3.81 | 3.81 |
| 409.40 | 3.43 | 3.43 |