Basic Information
ID: ALA3868338
Type: Binding
Description: Displacement of (2S)-N-(2-phenylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX1 receptor Ile408-Val mutant expressed on CHO cell membrane measured after 3 hrs by TopCount method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3868338
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.65 | 5.13 | 5.13 |
| 435.43 | 3.74 | 3.74 |
| 386.37 | 4.30 | 4.30 |
| 447.88 | 4.52 | 4.52 |
| 408.41 | 4.04 | 4.04 |
| 434.45 | 4.35 | 4.35 |
| 436.42 | 3.14 | 3.14 |
| 419.43 | 4.71 | 4.71 |
| 408.41 | 4.04 | 4.04 |
| 408.41 | 3.81 | 3.81 |
| 425.40 | 3.34 | 3.34 |
| 398.41 | 4.17 | 4.17 |
| 409.40 | 3.43 | 3.43 |
| 435.43 | 3.74 | 3.74 |
| 446.46 | 4.62 | 4.62 |
| 408.41 | 4.04 | 4.04 |
| 441.46 | 3.81 | 3.81 |
| 435.43 | 3.74 | 3.74 |
| 435.43 | 3.74 | 3.74 |
| 420.49 | 4.31 | 4.31 |
| 408.41 | 4.04 | 4.04 |
| 435.43 | 3.74 | 3.74 |
| 434.45 | 4.55 | 4.55 |
| 368.38 | 4.16 | 4.16 |
| 434.39 | 4.45 | 4.45 |
| 408.41 | 3.81 | 3.81 |
| 453.37 | 3.61 | 3.61 |
| 435.43 | 3.74 | 3.74 |
| 436.42 | 3.14 | 3.14 |
| 382.41 | 4.47 | 4.47 |
| 413.48 | 3.89 | 3.89 |
| 408.41 | 3.81 | 3.81 |
| 308.29 | 1.11 | 1.11 |
| 434.45 | 4.35 | 4.35 |
| 386.37 | 4.30 | 4.30 |
| 453.37 | 3.61 | 3.61 |
| 416.40 | 4.31 | 4.31 |
| 385.37 | 2.59 | 2.59 |
| 408.41 | 3.81 | 3.81 |
| 407.42 | 4.64 | 4.64 |
| 399.45 | 3.50 | 3.50 |
| 409.40 | 3.43 | 3.43 |
| 436.42 | 3.14 | 3.14 |
| 398.41 | 4.17 | 4.17 |
| 386.37 | 4.30 | 4.30 |
| 453.37 | 3.61 | 3.61 |
| 408.41 | 4.04 | 4.04 |
| 435.43 | 3.74 | 3.74 |