Assay Report Card

Basic Information

ID: ALA3868486

Type: Binding

Description: Inhibition of HCV genotype 1a NS3/4A protease assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition measured after 2.5 hrs by time-resolved fluorescence assay

Organism: Hepatitis C virus subtype 1a

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
766.923.303.30
833.935.075.07
832.035.155.15
846.065.685.68
820.025.005.00
791.974.224.22
834.055.395.39
846.065.545.54
805.994.614.61
793.984.454.45