Basic Information
ID: ALA3868492
Type: Binding
Description: Inhibition of HCV genotype 1b NS3/4A protease A156T mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition measured after 2.5 hrs by time-resolved fluorescence assay
Organism: Hepatitis C virus subtype 1b
Activity Charts
Bioactivity
Activity Types for Assay ALA3868492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 766.92 | 3.30 | 3.30 |
| 833.93 | 5.07 | 5.07 |
| 832.03 | 5.15 | 5.15 |
| 846.06 | 5.68 | 5.68 |
| 820.02 | 5.00 | 5.00 |
| 791.97 | 4.22 | 4.22 |
| 834.05 | 5.39 | 5.39 |
| 846.06 | 5.54 | 5.54 |
| 805.99 | 4.61 | 4.61 |
| 793.98 | 4.45 | 4.45 |