Basic Information
ID: ALA3868516
Type: ADME
Description: Agonist activity at human LXR-alpha expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assay relative to pan agonist 1-(2,4-difluorobenzyl)-2-oxo-6-(4-phenoxyphenyl)-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile
Organism: Homo sapiens
Cell type: CV-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3868516
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.07 | 6.15 | 6.15 |
| 543.52 | 6.80 | 6.80 |
| 625.98 | 7.09 | 7.09 |
| 539.10 | 5.64 | 5.64 |
| 593.07 | 6.06 | 6.06 |
| 575.08 | 5.92 | 5.92 |
| 591.53 | 6.43 | 6.43 |
| 540.63 | 5.27 | 5.27 |
| 557.09 | 5.78 | 5.78 |
| 609.52 | 6.57 | 6.57 |
| 595.50 | 6.40 | 6.40 |
| 575.08 | 5.92 | 5.92 |
| 511.04 | 4.91 | 4.91 |
| 553.12 | 6.20 | 6.20 |
| 563.48 | 5.70 | 5.70 |