Assay Report Card

Basic Information

ID: ALA3868545

Type: Functional

Description: In vivo agonist activity at LXR-beta in cynomolgus monkey assessed as ABCG1 gene induction by measuring total RNA level at 1 mg/kg, po qd administered via gavage for 14 days measured after 5 to 6 hrs of last-dose relative to control

Organism: Macaca fascicularis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
609.526.576.57
575.085.925.92