Basic Information
ID: ALA3869551
Type: Functional
Description: Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhibited forskolin-stimulated cAMP formation after 20 mins by HTRF assay
Organism: Homo sapiens
Cell type: AV12
Activity Charts
Bioactivity
Activity Types for Assay ALA3869551
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 359.74 | 0.47 | 0.47 |
| 376.19 | 0.98 | 0.98 |
| 417.25 | 1.13 | 1.13 |
| 376.19 | 0.98 | 0.98 |
| 339.32 | 0.12 | 0.12 |
| 375.21 | 0.95 | 0.95 |
| 401.21 | 2.30 | 2.30 |
| 433.24 | 1.35 | 1.35 |
| 376.19 | 0.98 | 0.98 |
| 473.34 | 1.91 | 1.91 |
| 341.75 | 0.33 | 0.33 |
| 307.30 | -0.32 | -0.32 |
| 327.74 | 1.77 | 1.77 |
| 378.18 | 1.96 | 1.96 |
| 459.31 | 1.90 | 1.90 |
| 341.75 | 0.33 | 0.33 |
| 458.32 | 2.51 | 2.51 |
| 376.19 | 0.98 | 0.98 |