Assay Report Card

Basic Information

ID: ALA3869554

Type: Functional

Description: Agonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as increase in forskolin-stimulated cAMP formation up to 25 uM after 20 mins by HTRF assay

Organism: Homo sapiens

Cell type: AV12

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
359.740.470.47
376.190.980.98
417.251.131.13
376.190.980.98
339.320.120.12
375.210.950.95
401.212.302.30
433.241.351.35
376.190.980.98
473.341.911.91
341.750.330.33
307.30-0.32-0.32
378.181.961.96
459.311.901.90
341.750.330.33
458.322.512.51
376.190.980.98