Assay Report Card

Basic Information

ID: ALA3870144

Type: ADME

Description: Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid at 10 ug/ml measured after 6 hrs relative to control

Organism: Chlorocebus aethiops

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.233.173.17
274.322.642.64
350.463.973.97
364.454.394.39
443.384.764.76
364.494.004.00
364.454.394.39
364.454.394.39
429.364.734.73
338.202.902.90
440.595.575.57
372.223.723.72
314.433.283.28