Basic Information
ID: ALA3870654
Type: Binding
Description: Inhibition of human recombinant GST-tagged Atg4B expressed in Escherichia coli assessed as uncleaved substrate level at 500 uM using LC3B-GST as substrate after 6 mins by SDS-PAGE assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3870654
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 175.19 | 1.68 | 1.68 |
| 275.26 | 1.90 | 1.90 |
| 293.32 | 3.28 | 3.28 |
| 289.29 | 2.29 | 2.29 |
| 390.44 | 3.98 | 3.98 |
| 458.39 | 4.09 | 4.09 |
| 383.45 | 5.26 | 5.26 |
| 414.50 | 4.37 | 4.37 |
| 426.47 | 4.84 | 4.84 |
| 273.33 | 3.62 | 3.62 |
| 360.29 | 1.39 | 1.39 |
| 416.36 | 1.30 | 1.30 |
| 346.26 | 1.00 | 1.00 |
| 387.23 | 3.91 | 3.91 |
| 280.28 | 2.75 | 2.75 |
| 359.38 | 4.27 | 4.27 |
| 564.64 | 5.90 | 5.90 |
| 369.37 | 3.14 | 3.14 |
| 343.77 | 3.20 | 3.20 |
| 314.39 | 2.96 | 2.96 |
| 273.24 | 1.68 | 1.68 |
| 438.48 | 4.26 | 4.26 |
| 375.38 | 3.30 | 3.30 |
| 280.28 | 2.75 | 2.75 |
| 273.29 | 2.08 | 2.08 |
| 386.45 | 3.69 | 3.69 |
| 309.32 | 3.36 | 3.36 |
| 444.49 | 5.85 | 5.85 |
| 360.41 | 3.34 | 3.34 |
| 302.37 | 2.68 | 2.68 |
| 418.45 | 2.95 | 2.95 |
| 310.31 | 1.94 | 1.94 |
| 350.34 | 1.82 | 1.82 |
| 337.33 | 2.93 | 2.93 |
| 285.26 | 0.80 | 0.80 |
| 353.44 | 4.02 | 4.02 |
| 340.36 | 0.52 | 0.52 |
| 330.34 | 3.90 | 3.90 |
| 450.41 | 3.65 | 3.65 |
| 402.49 | 4.52 | 4.52 |
| 323.35 | 2.86 | 2.86 |
| 405.19 | 3.96 | 3.96 |
| 372.22 | 4.05 | 4.05 |
| 315.37 | 1.38 | 1.38 |
| 543.89 | 1.36 | 1.36 |
| 337.38 | 3.16 | 3.16 |
| 392.46 | 4.27 | 4.27 |
| 369.37 | 3.14 | 3.14 |
| 324.34 | 2.33 | 2.33 |
| 310.31 | 1.94 | 1.94 |
| 478.43 | 2.98 | 2.98 |
| 331.33 | 3.30 | 3.30 |
| 283.29 | 1.94 | 1.94 |
| 339.35 | 2.04 | 2.04 |
| 362.39 | 3.20 | 3.20 |
| 304.31 | 3.23 | 3.23 |
| 332.36 | 3.76 | 3.76 |
| 354.38 | 3.01 | 3.01 |
| 429.40 | 1.38 | 1.38 |
| 464.52 | 4.19 | 4.19 |
| 436.39 | 3.25 | 3.25 |
| 272.30 | 1.79 | 1.79 |
| 242.23 | 1.95 | 1.95 |
| 388.34 | 2.17 | 2.17 |
| 422.36 | 2.81 | 2.81 |
| 419.44 | 4.49 | 4.49 |
| 345.36 | 3.74 | 3.74 |
| 321.38 | 4.06 | 4.06 |
| 315.27 | 3.63 | 3.63 |
| 392.46 | 2.44 | 2.44 |
| 374.32 | 1.78 | 1.78 |
| 440.50 | 4.85 | 4.85 |
| 314.39 | 2.96 | 2.96 |
| 392.46 | 4.27 | 4.27 |
| 261.23 | 1.51 | 1.51 |
| 308.34 | 3.15 | 3.15 |
| 318.33 | 3.84 | 3.84 |
| 492.45 | 3.37 | 3.37 |
| 284.27 | 2.65 | 2.65 |
| 391.30 | 4.07 | 4.07 |
| 416.40 | 2.95 | 2.95 |
| 464.40 | 2.59 | 2.59 |
| 297.20 | 1.22 | 1.22 |
| 422.48 | 5.02 | 5.02 |
| 385.42 | 4.79 | 4.79 |
| 279.30 | 3.35 | 3.35 |
| 429.86 | 1.60 | 1.60 |
| 300.36 | 2.57 | 2.57 |
| 285.34 | 3.62 | 3.62 |
| 529.98 | 3.01 | 3.01 |
| 407.47 | 3.82 | 3.82 |
| 406.48 | 4.66 | 4.66 |
| 329.40 | 1.73 | 1.73 |
| 480.44 | 5.55 | 5.55 |
| 401.46 | 2.59 | 2.59 |
| 496.56 | 4.45 | 4.45 |
| 334.34 | 2.42 | 2.42 |
| 356.81 | 3.48 | 3.48 |
| 432.52 | 5.19 | 5.19 |
| 323.35 | 2.86 | 2.86 |
| 495.52 | 2.75 | 2.75 |
| 348.36 | 2.81 | 2.81 |
| 346.38 | 2.95 | 2.95 |
| 388.22 | 3.31 | 3.31 |
| 337.42 | 4.26 | 4.26 |
| 420.51 | 5.05 | 5.05 |
| 310.31 | 1.94 | 1.94 |
| 415.49 | 3.03 | 3.03 |
| 392.46 | 4.27 | 4.27 |
| 324.34 | 2.13 | 2.13 |
| 456.50 | 4.93 | 4.93 |
| 257.29 | 2.62 | 2.62 |
| 352.39 | 2.84 | 2.84 |
| 276.29 | 0.62 | 0.62 |
| 344.76 | 2.60 | 2.60 |
| 315.37 | 1.29 | 1.29 |
| 530.62 | 5.01 | 5.01 |
| 353.31 | 3.31 | 3.31 |
| 343.77 | 3.77 | 3.77 |
| 337.38 | 2.27 | 2.27 |
| 391.47 | 2.86 | 2.86 |
| 378.43 | 3.88 | 3.88 |
| 402.33 | 0.91 | 0.91 |
| 361.42 | 5.08 | 5.08 |
| 448.56 | 5.83 | 5.83 |
| 336.39 | 2.87 | 2.87 |
| 440.50 | 4.85 | 4.85 |
| 323.30 | 3.05 | 3.05 |
| 310.31 | 1.94 | 1.94 |
| 442.46 | 4.70 | 4.70 |
| 440.50 | 5.23 | 5.23 |
| 323.35 | 2.94 | 2.94 |
| 323.30 | 3.05 | 3.05 |
| 283.33 | 3.23 | 3.23 |
| 474.51 | 3.45 | 3.45 |
| 325.39 | 3.83 | 3.83 |
| 385.42 | 4.79 | 4.79 |
| 436.51 | 4.43 | 4.43 |
| 388.46 | 4.13 | 4.13 |
| 422.36 | 2.86 | 2.86 |
| 433.34 | 3.23 | 3.23 |
| 378.21 | 4.43 | 4.43 |
| 393.45 | 1.84 | 1.84 |
| 367.40 | 4.85 | 4.85 |
| 345.40 | 0.96 | 0.96 |
| 444.41 | 2.08 | 2.08 |
| 454.53 | 5.24 | 5.24 |
| 355.39 | 5.02 | 5.02 |
| 406.48 | 4.66 | 4.66 |
| 307.35 | 3.67 | 3.67 |
| 426.47 | 4.46 | 4.46 |
| 334.34 | 2.42 | 2.42 |
| 281.27 | 2.14 | 2.14 |
| 304.35 | 1.40 | 1.40 |
| 494.47 | 5.94 | 5.94 |
| 318.33 | 3.84 | 3.84 |
| 311.31 | 3.42 | 3.42 |
| 550.61 | 5.51 | 5.51 |
| 367.36 | 1.68 | 1.68 |
| 343.77 | 3.77 | 3.77 |
| 426.47 | 4.93 | 4.93 |
| 525.54 | 2.36 | 2.36 |
| 356.42 | 3.29 | 3.29 |
| 325.26 | 2.26 | 2.26 |
| 330.34 | 3.90 | 3.90 |
| 400.35 | 2.04 | 2.04 |
| 412.45 | 4.53 | 4.53 |
| 408.45 | 4.63 | 4.63 |
| 343.38 | 4.44 | 4.44 |
| 388.30 | 0.52 | 0.52 |
| 418.49 | 4.80 | 4.80 |
| 309.32 | 2.55 | 2.55 |
| 343.77 | 3.77 | 3.77 |
| 436.51 | 5.41 | 5.41 |
| 377.32 | 3.57 | 3.57 |
| 406.48 | 4.66 | 4.66 |
| 488.54 | 3.84 | 3.84 |
| 408.45 | 4.38 | 4.38 |