Basic Information
ID: ALA3871365
Type: Binding
Description: Inhibition of 15-LOX-1 in C57bl/6 mouse precision-cut lung slices assessed as reduction in LPS-stimulated IL-1beta mRNA expression level at 50 uM incubated for 20 hrs followed by LPS stimulation for 4 hrs in presence of linoleic acid by RT-qPCR analysis
Format: BAO_0000019
Organism: Mus musculus
Strain: C57bl/6
Target: Arachidonate 15-lipoxygenase(ALA3259476)
Document: ALA3871264
Inhibition of 15-LOX-1 in C57bl/6 mouse precision-cut lung slices assessed as reduction in LPS-stimulated IL-1beta mRNA expression level at 50 uM incubated for 20 hrs followed by LPS stimulation for 4 hrs in presence of linoleic acid by RT-qPCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3871365
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.39 | 3.53 | 3.53 |