Basic Information
ID: ALA3872637
Type: Binding
Description: Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate after 30 mins in presence of catalase by methylene blue dye based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3872637
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.14 | 2.69 | 2.69 |
| 262.27 | 2.24 | 2.24 |
| 248.24 | 1.93 | 1.93 |
| 293.24 | 1.84 | 1.84 |
| 218.26 | 1.13 | 1.13 |
| 218.26 | 1.13 | 1.13 |
| 266.23 | 2.07 | 2.07 |
| 282.69 | 2.58 | 2.58 |
| 266.23 | 2.07 | 2.07 |
| 284.22 | 2.21 | 2.21 |
| 282.69 | 2.58 | 2.58 |