Assay Report Card

Basic Information

ID: ALA3872680

Type: Functional

Description: Downregulation of CDK2 expression in human K562/ADR cells assessed as ratio of CDK2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SP600125 for 1 hr followed by compound addition measured after 48 hrs by Western blot analysis (Rvb = 0.65 No_unit)

Organism: Homo sapiens

Cell type: K562/Adr

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
508.483.873.87