Basic Information
ID: ALA3872681
Type: Functional
Description: Downregulation of CDK2 expression in human K562/ADR cells assessed as ratio of CDK2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SB203580 for 1 hr followed by compound addition measured after 48 hrs by Western blot analysis (Rvb = 0.65 No_unit)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562/Adr
Target: Molecular identity unknown(ALA612546)
Document: ALA3872207
Downregulation of CDK2 expression in human K562/ADR cells assessed as ratio of CDK2 to beta-actin level at 0.1 uM pretreated with MAPK inhibitor SB203580 for 1 hr followed by compound addition measured after 48 hrs by Western blot analysis (Rvb = 0.65 No_unit): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3872681
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.48 | 3.87 | 3.87 |