Assay Report Card

Basic Information

ID: ALA3872978

Type: Binding

Description: Noncompetitive inhibition of Leishmania major recombinant N-terminal hexa-His tagged PTR1 catalytic activity expressed in Escherichia coli BL21(DE3) assessed as decrease in thermal shift stabilization at 50 uM at pH 4.7 in presence of varying levels of NADPH and constant biopterin substrate concentration by SYPRO orange dye based assay

Organism: Leishmania major

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
334.583.133.13