Basic Information
ID: ALA3873322
Type: Binding
Description: Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production at 50 uM preincubated with enzyme followed by arachidonic acid substrate addition by UV-vis spectrophotometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3873322
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 379.89 | 5.68 | 5.68 |
| 254.24 | 2.87 | 2.87 |
| 270.24 | 2.58 | 2.58 |
| 222.24 | 3.46 | 3.46 |
| 268.27 | 3.17 | 3.17 |
| 268.27 | 3.17 | 3.17 |
| 284.27 | 2.88 | 2.88 |
| 284.27 | 2.88 | 2.88 |
| 238.24 | 3.17 | 3.17 |
| 238.24 | 3.17 | 3.17 |
| 358.35 | 3.20 | 3.20 |
| 328.32 | 3.19 | 3.19 |
| 312.32 | 3.49 | 3.49 |
| 268.27 | 3.17 | 3.17 |
| 254.24 | 2.87 | 2.87 |