Basic Information
ID: ALA3873332
Type: Binding
Description: Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production at 50 uM preincubated for 2 hrs followed by TNF-alpha addition for 24 hrs by ELISA
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA3873332
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 254.24 | 2.87 | 2.87 |
| 270.24 | 2.58 | 2.58 |
| 222.24 | 3.46 | 3.46 |
| 268.27 | 3.17 | 3.17 |
| 268.27 | 3.17 | 3.17 |
| 284.27 | 2.88 | 2.88 |
| 284.27 | 2.88 | 2.88 |
| 238.24 | 3.17 | 3.17 |
| 238.24 | 3.17 | 3.17 |
| 358.35 | 3.20 | 3.20 |
| 328.32 | 3.19 | 3.19 |
| 312.32 | 3.49 | 3.49 |
| 268.27 | 3.17 | 3.17 |
| 254.24 | 2.87 | 2.87 |