Basic Information
ID: ALA3873874
Type: Functional
Description: Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of glutamate-induced intracellular calcium level measured after 24 to 48 hrs by FLIPR assay
Organism: Homo sapiens
Cell type: AV12
Activity Charts
Bioactivity
Activity Types for Assay ALA3873874
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.45 | 5.01 | 5.01 |
| 416.44 | 4.45 | 4.45 |
| 417.43 | 3.85 | 3.85 |
| 445.48 | 4.49 | 4.49 |
| 445.48 | 4.49 | 4.49 |
| 445.48 | 4.49 | 4.49 |
| 445.48 | 4.49 | 4.49 |
| 445.48 | 4.49 | 4.49 |
| 437.84 | 4.19 | 4.19 |
| 421.45 | 5.01 | 5.01 |
| 437.84 | 4.19 | 4.19 |
| 421.39 | 3.68 | 3.68 |
| 445.48 | 4.49 | 4.49 |
| 471.40 | 4.56 | 4.56 |
| 471.40 | 4.56 | 4.56 |
| 445.48 | 4.49 | 4.49 |