Basic Information
ID: ALA3875317
Type: Binding
Description: Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in BL21(DE3)pLysS cells assessed as inhibition of DNA supercoiling activity in presence of ATP measured after 30 mins by malachite green dye based assay
Organism: Mycolicibacterium smegmatis
Activity Charts
Bioactivity
Activity Types for Assay ALA3875317
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 137.14 | -0.31 | -0.31 |
| 612.63 | 3.63 | 3.63 |
| 822.95 | 4.34 | 4.34 |
| 463.37 | 2.85 | 2.85 |
| 429.43 | 1.05 | 1.05 |
| 467.78 | 3.50 | 3.50 |
| 394.48 | 1.55 | 1.55 |
| 447.37 | 3.15 | 3.15 |
| 433.34 | 2.85 | 2.85 |
| 446.47 | 2.87 | 2.87 |
| 399.41 | 1.04 | 1.04 |
| 447.37 | 3.15 | 3.15 |
| 466.89 | 3.21 | 3.21 |
| 451.33 | 2.98 | 2.98 |
| 412.47 | 1.69 | 1.69 |
| 428.92 | 2.20 | 2.20 |
| 463.37 | 2.85 | 2.85 |
| 417.40 | 1.18 | 1.18 |
| 462.47 | 2.57 | 2.57 |
| 433.85 | 1.69 | 1.69 |
| 396.47 | 1.99 | 1.99 |
| 488.56 | 3.26 | 3.26 |
| 412.47 | 1.69 | 1.69 |
| 382.44 | 1.68 | 1.68 |
| 433.34 | 2.85 | 2.85 |
| 400.43 | 1.82 | 1.82 |
| 500.60 | 3.13 | 3.13 |
| 484.60 | 3.43 | 3.43 |
| 364.45 | 1.54 | 1.54 |
| 382.44 | 1.68 | 1.68 |
| 467.78 | 3.50 | 3.50 |
| 424.50 | 1.56 | 1.56 |
| 451.33 | 2.98 | 2.98 |
| 450.44 | 2.70 | 2.70 |
| 413.43 | 1.35 | 1.35 |
| 378.48 | 1.85 | 1.85 |
| 416.88 | 2.33 | 2.33 |
| 505.02 | 3.77 | 3.77 |
| 470.57 | 3.12 | 3.12 |
| 408.50 | 1.86 | 1.86 |
| 432.45 | 2.56 | 2.56 |
| 398.89 | 2.19 | 2.19 |
| 394.48 | 1.55 | 1.55 |