Basic Information
ID: ALA3875318
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis
Organism: Mycobacterium tuberculosis
Activity Charts
Bioactivity
Activity Types for Assay ALA3875318
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 137.14 | -0.31 | -0.31 |
| 612.63 | 3.63 | 3.63 |
| 822.95 | 4.34 | 4.34 |
| 472.51 | 2.99 | 2.99 |
| 463.37 | 2.85 | 2.85 |
| 434.44 | 4.03 | 4.03 |
| 441.54 | 3.39 | 3.39 |
| 445.89 | 3.57 | 3.57 |
| 429.43 | 1.05 | 1.05 |
| 467.78 | 3.50 | 3.50 |
| 414.92 | 3.97 | 3.97 |
| 394.48 | 1.55 | 1.55 |
| 447.37 | 3.15 | 3.15 |
| 433.34 | 2.85 | 2.85 |
| 484.96 | 4.85 | 4.85 |
| 461.96 | 3.74 | 3.74 |
| 446.47 | 2.87 | 2.87 |
| 399.41 | 1.04 | 1.04 |
| 456.44 | 2.83 | 2.83 |
| 447.37 | 3.15 | 3.15 |
| 466.89 | 3.21 | 3.21 |
| 451.33 | 2.98 | 2.98 |
| 385.92 | 3.94 | 3.94 |
| 412.47 | 1.69 | 1.69 |
| 428.92 | 2.20 | 2.20 |
| 463.37 | 2.85 | 2.85 |
| 416.89 | 3.54 | 3.54 |
| 479.44 | 3.94 | 3.94 |
| 417.40 | 1.18 | 1.18 |
| 416.96 | 3.83 | 3.83 |
| 495.51 | 4.10 | 4.10 |
| 462.47 | 2.57 | 2.57 |
| 433.85 | 1.69 | 1.69 |
| 396.47 | 1.99 | 1.99 |
| 468.89 | 4.68 | 4.68 |
| 488.56 | 3.26 | 3.26 |
| 400.89 | 3.66 | 3.66 |
| 430.99 | 4.14 | 4.14 |
| 412.47 | 1.69 | 1.69 |
| 461.96 | 3.74 | 3.74 |
| 318.77 | 5.85 | 5.85 |
| 405.45 | 4.00 | 4.00 |
| 439.89 | 4.65 | 4.65 |
| 382.44 | 1.68 | 1.68 |
| 433.34 | 2.85 | 2.85 |
| 371.89 | 3.63 | 3.63 |
| 400.43 | 1.82 | 1.82 |
| 500.60 | 3.13 | 3.13 |
| 448.47 | 4.34 | 4.34 |
| 450.51 | 4.19 | 4.19 |
| 382.45 | 2.89 | 2.89 |
| 484.60 | 3.43 | 3.43 |
| 435.34 | 4.32 | 4.32 |
| 364.45 | 1.54 | 1.54 |
| 419.47 | 4.31 | 4.31 |
| 382.44 | 1.68 | 1.68 |
| 467.78 | 3.50 | 3.50 |
| 427.44 | 2.80 | 2.80 |
| 427.51 | 3.08 | 3.08 |
| 464.54 | 4.50 | 4.50 |
| 425.47 | 3.23 | 3.23 |
| 424.50 | 1.56 | 1.56 |
| 451.33 | 2.98 | 2.98 |
| 411.44 | 2.92 | 2.92 |
| 450.44 | 2.70 | 2.70 |
| 413.43 | 1.35 | 1.35 |
| 378.48 | 1.85 | 1.85 |
| 416.89 | 3.54 | 3.54 |
| 416.88 | 2.33 | 2.33 |
| 302.31 | 5.34 | 5.34 |
| 505.02 | 3.77 | 3.77 |
| 445.89 | 3.57 | 3.57 |
| 406.34 | 4.29 | 4.29 |
| 470.57 | 3.12 | 3.12 |
| 451.40 | 4.48 | 4.48 |
| 408.50 | 1.86 | 1.86 |
| 432.45 | 2.56 | 2.56 |
| 398.89 | 2.19 | 2.19 |
| 450.44 | 3.91 | 3.91 |
| 394.48 | 1.55 | 1.55 |
| 396.47 | 3.20 | 3.20 |