Basic Information
ID: ALA3875323
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins in presence of ATP by ethidium bromide staining based agarose gel electrophoresis
Format: BAO_0000019
Organism: Mycobacterium tuberculosis
Target: DNA gyrase subunit A/DNA gyrase subunit B(ALA3430898)
Document: ALA3875146
Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins in presence of ATP by ethidium bromide staining based agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3875323
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 172.18 | 2.01 | 2.01 |
| 188.18 | 1.64 | 1.64 |
| 374.35 | 3.11 | 3.11 |
| 374.35 | 3.11 | 3.11 |
| 374.35 | 3.25 | 3.25 |
| 192.21 | 1.71 | 1.71 |